New Balance 1500的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列股價、配息、目標價等股票新聞資訊

The Bulldog

為了解決New Balance 1500的問題，作者Williams, John 這樣論述：

In this book you will learn all the main aspects of properly raising and caring for a Bulldog. The book covers the origin of this breed and the proper way to train this beautiful dog. You will learn about the Bulldog's temperament, its important history and the maintenance and training your dog will

need. This book teaches how to avoid mistakes in training due to not understanding the temperament of the Bulldog breed. Finally, many breeds have their own ailments and the Bulldog is no different. You will learn about the various ailments of the Bulldog and what to look for as it ages. Your Bulld

og makes a great watchdog, courageous to a fault when it comes to defending his family and territory, albeit very sweet and sociable. Instead of being lively, he is as dignified as his expression suggests, with a kind and sometimes stubborn, nature. Easygoing and friendly, your Bulldog will get alon

g with everyone. He can be slow to learn. However, once he has learned something, he'll never forget it. Rarely a barker, his appearance is enough to scare off any possible intruders. The Bulldog is very different from the mastiff-type dogs who were his ancestors. The breed was entirely developed in

Old England. First mentioned in 1500, the fierce dogs were utilized in what was known as bull-baiting, both a practical activity as well as a popular sport where the dog would grab a bull's nose and roughly shake it, causing the bull to lose its balance and fall to the ground where the dog held tig

ht to keep the animal pinned. After Bulldogs came to the U.S., one by the name of Donald - a brindle and white Bulldog - was shown in 1880 in New York. In 1886, Bob, another Bulldog, was registered with the AKC. H.D. Kendall, from Lowell Massachusetts, formed the Bulldog Club of America in 1890. At

first, this club used the English breed standard, but felt it wasn't exact enough for them. In 1894, they put together an American standard for the American-bred Bulldog. The British reacted in protest to the name, along with some of the details of the new standard. Over time, the standard was re-do

ne and came to be accepted in 1896; it is still the standard today. In 1890, the AKC recognized the Bulldog breed. Bulldogs rose in popularity during the 1940s and 1950s so that they were near the top 10 breeds. According to the AKC, the breed ranks fifth out of different dog breeds and varieties th

at are listed in the AKC registry - a true tribute to his standing as a companion dog. Above all, the Bulldog breed as it is today stands as a triumphant example of the human ability to alter an entire breed, making it into an affectionate, desirable companion through dedicated, careful breeding pra

ctice. During the 1800s, some cities - like Rome - had laws forbidding Bulldogs to be walked on the streets, even leashed, because of how ferocious they were. Yet, only a few years later, the Bulldog was becoming known as a most tranquil and friendly dog; all due to some very dedicated, patient, kno

wledgeable breeders with a vision of how a Bulldog could be at its best. He can live literally anywhere, adores children, is loyal and affection and very easy to care for. In fact, the Bulldog, today, is probably one of the gentlest dogs there are. Have your new pup checked by a vet within a few day

s of his coming home with you. Your vet can then advise you concerning general healthcare of your Bulldog, feeding, preventing heartworms, deworming and vaccinations. Until he's had all his vaccines, always carry your Bulldog in a crate or in your arms when you take him to the vet. As with anything

worthwhile, owning a dog involves not only pleasure and company, but responsibility as well. The fun parts are obvious, but you must also be aware of the responsibilities, not only for your dog, but also for other people and the neighborhood or anything around him. Owning a dog requires a conscious

approach to everything that is in his/her environment. John Williams - A 25+ year aviation professional, pet enthusiast, musician and writer who with a team of professionals produce informative books with refreshing content and style. I have published five titles so far: ＂Take Charge of Your Aviat

ion Career＂, ＂Bichon Frise - Unique Among Dogs,＂ ＂Pomeranian - Breed Of A Queen,＂ ＂The Boxer Scholar And Clown,＂ ＂German Shepherd: Loyal, Powerful And Noble＂ and now ＂The Bulldog.＂ We pride ourselves on producing quality products that will educate and entertain our readers. It is our desire to add v

alue to the marketplace in a new and fresh way. For more author information, kindly go to the author website: www.amazon.com/author/john_williams. Thank you!

New Balance 1500進入發燒排行的影片

氣體擴散層經聚四氟乙烯處理對其親疏水性平衡以及燃料電池效能之影響

為了解決New Balance 1500的問題，作者謝淳凱 這樣論述：

氣體擴散層（Gas Diffusion Layer；GDL）為質子交換膜燃料電池（Proton Exchange Membrane Fuel Cell；PEMFC）的重要元件之一，而氣體擴散層作為氣體、電子、質子與產物水的傳輸通道，需要具備高導電性、透氣性、疏水性、抗腐蝕性及強度等特性。本研究著重於氣體擴散層疏水性的提升，尋找到良好的疏水性與親水性的平衡，目前商業用的氣體擴散層在進行疏水處理時，僅會在氣體擴散層的一側添加疏水層，並沒有考慮到氣體擴散層本身疏水性的需求。而本研究先將PAN系氧化纖維氈進行 1000℃ 碳化，並含浸酚醛樹脂再進行熱壓，而得到碳纖維紙作為本實驗的基材，以不同濃度的疏

水漿料—聚四氟乙烯（Polytetrafluoroethylene；PTFE）來浸泡碳纖維紙，使聚四氟乙烯填充進入碳纖維紙中的間隙，適度的調整結構特性以及電化學表現。此製程最主要可使氣體擴散層的疏水性提升，PTFE 添加的多寡會影響燃料電池在反應過程中的產物水排除的難易程度，所以適度的水管理能力可以提升電池的性能表現。在實驗使用了兩種不同的碳纖維紙原料，分別為 165 克 GDL 與 230 克 GDL，並且最佳的 PTFE 濃度參數皆為 C%，並在負載 0.3 V 下，最大電流密度分別為 1391 mA/cm2以及2389 mA/cm2，最大功率密度為 443 mW/cm2 以及 762 m

W/cm2。

The Greater China Factbook 大中華百科全書

為了解決New Balance 1500的問題，作者艾天望（德） 這樣論述：

　　本書作者艾天望係一名德籍人士，卻說的一口流利的國語、並在（台灣今日）德文雙月刊外籍編輯。 　　由於兩岸三地未能有一本可向外國介紹大中華包括亞洲華人的專書，於是五年前開始編寫，其間從蒐集資料並請美籍專家校對，下了很長的功夫，本來此種書應是由政府單位來籌劃出版的。可是如今卻由一名外籍人士獨立花了五年時間將此大中華百科全書編著完成。 　　內容資料包括人、事、史、時、地、物、等等。每一筆資料均是經過一查再查並諮詢過相關專家的確認。 　　這是一本英中對照的百科全書共685頁，在２1世紀是大中華圈的世紀，本書正可向世人推廣大中華圈的形成種種，2008年中國的奧運前，本百科全書正是推廣的好時機。 　　C

hina has a magnificent civilization that dates back at least 4000 years. Although the infra-structure in many parts of the Chinese mainland today remains underdeveloped, the country is now emerging and looks to become an ambitious superpower in the 21st century and as a new economic powerhouse in As

ia. Since undergoing economic reform in the 1980s, the People’s Republic of China (PRC) has transformed itself into a vibrant export economy that supplies the world with textiles, toys, household electronics and many other products. 　　Today, the PRC is a country of great contrasts. It is a developi

ng country where many people in rural areas subsist on an income of less than US＄ 1 a day, but is also as a nuclear power and a member of the exclusive club of nations with a manned space program. China is seen by some as a huge market and land of opportunity but regarded by others as a threat to th

e Asia-Pacific region and world peace—the PRC’s new economic and military might also creates concerns about a shift in the balance of power in East Asia, with worries particularly prevalent in Japan and the US. 　　The rise of the PRC has resulted in an enormous demand for information about the count

ry, its people, rulers, history and culture. This book presents basic information and the most relevant data about the greater China area in a single volume. It focuses on the China mainland (under administration of the PRC) and the Taiwan area (under administration of the Republic of China, abbrev.

ROC), since the mainstream culture in both the PRC and the ROC is unquestionably Chinese. To make this comprehensive reference book more useful, I have added traditional Chinese characters for all important terms as well as personal and geographical names. 　　Many important aspects of China and its

culture, like history, arts or religion, certainly deserve a much more detailed description than the cursory glance this book provides, but since I am trying to offer a general, brief introduction to all aspects, I had to focus on the most basic content. Why “Greater China”? 　　The political confl

ict that has existed across in the Taiwan Strait for decades proves that interpreting the term “China” is not easy—China is not only a geographical term, but also has political and cultural connotations. Over many years it has become common practice to use the word “China” as a substitute for the PR

C and vice versa. Although this is convenient, it remains a fact that the PRC is not completely identical with China. Tibet and Xinjiang are controlled by the PRC government, but a majority of the population in those places is not ethnic Chinese, and the mainstream culture in these two regions is no

t Chinese either. Tibet and Xinjiang were in-corporated into the Qing empire through an imperialist policy that was continued by the Chinese communists. On the other hand, Taiwan is culturally part of China, but not a province of the PRC. 　　Despite the fact that there are two states governing the g

reater China area, most available reference books about China deal with the PRC only. The political rift between the PRC and the ROC, combined with Taiwan’s diplomatic isolation in the international arena, seems sufficient reason to many authors to exclude Taiwan from books about China. The title of

my book “The Greater China Factbook” indicates that its content is not exclusively about the PRC, but also in-cludes Taiwan. I chose the term “greater China” instead of “China” deliberately to avoid mis-understandings, because the rulers of the PRC and the ROC disagree about the meaning of terms li

ke “China” or “nation”. For the PRC, China includes Taiwan—“there is only one China in the 　　world, Taiwan Province is an integral part of the territory of the PRC”, as Beijing puts it. Supporters of Taiwan independence, on the other hand, object to the claim that Taiwan belongs to China, and they

promote the establishment of a Taiwanese nation. 　　Taiwan’s relations with China have been difficult since 1945. After the end of Japanese colonial rule (1895-1945) when Taiwan became a part of the ROC, the people who had lived on the island for generations initially welcomed the Chinese government

but before long grew deeply dissatisfied with the rule of the KMT, as it was corrupt and oppressive. Since the 2-28 uprising in 1947 and the decade of bloody repression (sometimes referred to as “white terror”) that followed, a deep rift had grown between Taiwanese and the mainlanders living on the

island. 　　Since the 1970s the PRC has been continually pressuring Taiwan and maneuvering to isolate the ROC internationally, an approach that has failed to generate a desire among the people of Taiwan to unite with the mainland. In fact, the biggest factor contributing to the growth of the Taiwan

independence movement is probably Beijing’s policy towards Taiwan, and surveys have shown a growing number of people in Taiwan regard themselves not as Chinese, but as both Chinese and Taiwanese or as Taiwanese only, a sign that they are developing their own identity to differentiate themselves from

people on the mainland. As the communist regime continues to ignore the progressing democratization of the ROC and the feelings of the people in Taiwan, the future task of actually integrating Taiwan and China will prove to be extremely complicated, should Beijing ever gain control over the island

without first changing its attitude and authoritarian system. 　　Some readers, especially those favoring Taiwan independence, may resent the inclusion of Taiwan in a book about China and the listing of Taiwan among the Chinese provinces. They should understand that this book is definitely not a stat

ement about the “Taiwan question”, because it’s not I, but the people of Taiwan, who should have the last word in decisions about political unification between Taiwan and China or the declaration of an independent state. Yet regardless of the political factors, it is undeniable that the majority of

people living in Taiwan today have ethnic, cultural and linguistic roots in Mainland China (although it can be argued that people who have a shared culture and shared ethnic origin do not necessarily have to belong politically to one nation-state). Since the culture and the language of China and Tai

wan are so closely connected, a work about China like this one must not omit Taiwan. However, this book does not advocate the PRC’s “one China” principle either: Although Taiwan is culturally a part of China, it is not a part of the PRC, and according to surveys the majority of the people living in

Taiwan—which is becoming a vibrant and contentious democracy—do not want Taiwan to be annexed by the non-democratic PRC. 　　Other readers might believe that this book focuses too much on Taiwan or that Taiwan is getting much more attention here than other provinces like, say, Anhui or Zhejiang. They

should consider that in the world’s media and in most publications Taiwan is often neglected or ignored. The inclusion of facts and details about Taiwan in this book is an attempt to address that common imbalance. Ignoring Taiwan also risks a description of the cross-strait tensions that will repre

sent the PRC’s version of the issues instead of providing a multi-faceted analysis. 　　This book is intended to be non-partisan, so inevitably supporters of the CCP, the KMT/“blue camp” or the DPP/“green camp” will find content they might not like or agree with; I am aware that I cannot please every

body. For me, facts matter more than considerations of political correctness in the PRC, the ROC, or elsewhere. 　　As this book went to press, relations between China and Taiwan were still tense. It is impossible to predict the future development of cross-strait relations and whether that path will

eventually lead to unification or to Taiwan’s independence, but I sincerely hope a peaceful solution will be found that will ultimately benefit the people living in the Taiwan area. I also hope that the reader, irrespective of his or her political opinion, regards this book as what it is supposed to

be—a useful tool, a comprehensive database and a rich source of information about the greater China area. 　　． provides comprehensive information about China’s population, geography, politics, economy, history, the Chinese zodiac and lunar calendar, weights and measures, and many other topics 　　．

is subdivided into four parts—China today, the Chinese provinces, China’s history, and the Appendix 　　．contains all important terms as well as personal and geographical names with their Chinese names in both traditional characters and Hanyu Pinyin 　　． comprises 685 pages and 54 maps ‧ includes da

ta and information about mainland China, Taiwan, Hong Kong, and Macau 　　． is an indispensable, well-organized, and user-friendly reference for sinologists, businesspeople, tourists, and any-body interested in the greater China area Preface..........................................................

............................................................................................ Acknowledgements................................................................................................................................. Nomenclature................................................

.......................................................................................... Pronunciation guide to modern Chinese............................................................................................... The sounds of Mandarin Chinese............................................

.................................................... The syllables in Mandarin Chinese................................................................................................. The Chinese tones.................................................................................................

......................... Other popular romanization and transliteration systems............................................................ Comparative tables........................................................................................................................ Comparison Hanyu

Pinyin—Tongyong Pinyin............................................................................ Conversion table Wade Giles—Hanyu Pinyin—MPS................................................................. Part I：China today......................................................... Facts and sta

tistics about China.............................................................................................................. China’s population................................................................................................................................China’s demographic dev

elopment................................................................................................. Nationalities in China....................................................................................................................... Languages in China................................

.......................................................................................... Religions in China........................................................................................................................... China’s geography................................................

................................................................................ General features.............................................................................................................................. China’s topography.........................................................

................................................................ Rivers and lakes............................................................................................................................... Vegetation and cultivation / Land usage..................................................

.................................... Natural disasters.............................................................................................................................. China’s climate......................................................................................................

................................ Climatic data for select Chinese cities............................................................................................ Government and politics...............................................................................................................

........ PRC (People’s Republic of China).................................................................................................. —Political system of the PRC........................................................................................................ —The Chinese Communist P

arty (CCP)....................................................................................... —Presidents and Premiers of the PRC......................................................................................... —The Parliament and the Judiciary of the PRC...............................

........................................... —Ministries and agencies under the PRC State Council............................................................. —Governors/Chief Executives of Hong Kong since 1843 and of Macau since 1623......... ROC (Republic of China)...............................

................................................................................. —Political system of the ROC...................................................................................................... 4 —Major political parties of the ROC................................................

......................................... —Presidents of the ROC 1912-1948............................................................................................. —Presidents / Vice Presidents of the ROC since 1948............................................................. —Premiers / Head

s of the ROC’s Executive Yuan.................................................................... —Heads of the ROC’s four other Yuans since 1928................................................................... —Ministries and agencies under the ROC Executive Yuan................................

........................ —Complete ROC election results since 1989............................................................................... —Rulers and Governors of Taiwan since 1624........................................................................... Human rights in China............

......................................................................................................... Cross-strait relations....................................................................................................................... Territorial issues................................

.............................................................................................. —Disputed land borders of the PRC........................................................................................... —Islands with sovereignty claimed by both the PRC and ROC.....................

........................... —Islands under the effective control of the ROC..................................................................... China’s economy..................................................................................................................................China (P

RC)..................................................................................................................................... Taiwan (ROC)................................................................................................................................. Quantification of t

he economies in Greater China and Singapore........................................... Banking and finance...................................................................................................................... Part II：The Chinese provinces.................................. The provi

nces of China today.............................................................................................................. China’s administrative organization.............................................................................................. Ranking of China’s cities and province

s by population, area, and pop. density (2005)........ Administrative subdivisions in the PRC...................................................................................... Abbreviations of geographical names...................................................................................

...... Changes in China’s provincial composition since 1949............................................................. Provinces of the old ROC (1912-1949)............................................................................................... Obsolete geographical names.................

...................................................................................... Gazetteer—the Chinese provinces in detail........................................................................................ 　　1.Anhui安徽 (119); 2. Beijing北京 (121); 3. Chongqing重慶 (122); 4. Fujian福建 (124); 5

. Gansu甘肅 (126); 6. Guangdong廣東 (128); 7. Guangxi廣西 (131); 8. Guizhou貴州(134); 9. Hainan海南 (136); 10. Hebei河北 (137); 11. Heilongjiang黑龍江 (140); 12. He-nan河南 (143); 13. Hong Kong香港 (146); 14. Hubei湖北 (147); 15. Hunan湖南 (150); 16. Inner Mongolia內蒙古 (153); 17. Jiangsu江蘇 (156); 18. Jiangxi江西 (158); 19. J

ilin吉林 (160); 20. Liaoning遼寧 (162); 21. Macau澳門 (165); 22. Ningxia寧夏 (166); 23. Qing-hai青海 (168); 24. Shaanxi陜西 (170); 25. Shandong山東 (173); 26. Shanghai上海 (176); 27. Shanxi山西 (177); 28. Sichuan四川 (179); 29. Taiwan台灣 (183); 30. Tianjin天津 (187); 31. Tibet西藏 (188); 32. Xinjiang新疆 (190); 33. Yunnan雲南 (

193); 34. Zhejiang浙江 (196). A few words about Singapore (199) Part III：China’s history............................................... Chronology of Chinese dynasties....................................................................................................... Historical capitals.........

........................................................................................................................ The History of China: A Summary...................................................................................................... The emergence of humans in the China region

......................................................................... Neolithic China: the Yangshao and Longshan Cultures............................................................ The legendary Xia Dynasty and the mythical emperors............................................................

The Shang/Yin Dynasty (ca. 1500-1000 BC).............................................................................. The Zhou Dynasty (ca. 1000-221 BC)......................................................................................... Qin Dynasty (221-207 BC): Birth of a unified China....

............................................................ The Han Dynasty (207 BC – 220 AD)........................................................................................ Time of division between Han and Sui (220-589).....................................................................

The Sui Dynasty (589-618)............................................................................................................ The Tang Dynasty (618-907)......................................................................................................... Time of division between Tang

and Song (902-979)................................................................. The Song Dynasty (960-1279)....................................................................................................... The Mongols and the Yuan Dynasty (1279-1368).......................................

.............................. Ming Dynasty (1368-1644): Chinese rule restored..................................................................... The Manchus and the Qing Dynasty (1644-1911)..................................................................... Chronology of Greater China 1911-20

06........................................................................................... List of noteworthy persons in Greater China..................................................................................... Part IV：Appendix........................................................ J

apan, Korea and Vietnam: History and Geography.......................................................................... History of Japan........................................................................................................................... Prime Ministers of Japan since 1885..

.......................................................................................... Geographical names in Japan........................................................................................................ History of Korea...........................................................

............................................................... Leaders of Korea since 1948......................................................................................................... Geographical names in Korea..........................................................................

............................. Leaders of Vietnam since 1954.................................................................................................... Geographical names in Vietnam................................................................................................... Internat

ional geographical names and terms...................................................................................... The 194 countries of the world and their capitals..................................................................... Alternative country names in Chinese......................

................................................................... Obsolete country names................................................................................................................ Important geographic terms.....................................................................

.................................... Continents and intercontinental regions...................................................................................... Seas and oceans, gulfs and straits.................................................................................................. M

ajor lakes..................................................................................................................................... Major rivers.................................................................................................................................... Major mou

ntain ranges.................................................................................................................. Islands, islets, and archipelagos..................................................................................................... Other places, territories, and regio

ns............................................................................................ Transnational or disputed territories and regions....................................................................... U. S. states......................................................................

................................................................ Canada’s provinces and territories................................................................................................ Australia’s states and territories....................................................................

................................. Administrative division of the United Kingdom........................................................................ The French r?gions.......................................................................................................................... The

16 German states................................................................................................................... The Russian republics.................................................................................................................... Space terms.................

................................................................................................................... Selected time zones............................................................................................................................... Chinese holidays...................

................................................................................................................. The Chinese calendar........................................................................................................................... Yin and Yang, the Five Primary Elements,

the Ten Heavenly Stems...................................... The Chinese Zodiac: Twelve Animal Signs and Twelve Earthly Branches............................. The Ganzhi system.........................................................................................................................

The Eight Trigrams and 64 Hexagrams....................................................................................... The 24 Solar Terms and the Eight Festivals................................................................................ Data about the Chinese lunar calendar, length of Ch

inese lunar years 1900-2050................ Chinese family names........................................................................................................................... Single-character family names.................................................................................

...................... Two-character family names.......................................................................................................... Degrees of kinship............................................................................................................................

... Military rank........................................................................................................................................... Ranks in the PRC Armed Forces.................................................................................................. Ranks in the

ROC Armed Forces................................................................................................. Weights and measures.......................................................................................................................... Chinese system..........................

.................................................................................................... Metric system................................................................................................................................. US/British system.....................................

.................................................................................... Other important measures............................................................................................................. Useful conversion tables.......................................................

......................................................... List of chemical elements...................................................................................................................... Excerpts from important documents...............................................................

.................................... Treaty of Shimonoseki (1895)....................................................................................................... ~ in Chinese: 馬關條約（下關條約）.................................................................................... Japan’s “21 Demands

” to China [full text] (1915)....................................................................... ~ in Chinese：日本的《二十一條要求》【全文】................................................................ Cairo Declaration [full text] (1943)....................................................................

............................ Agreements reached at the Yalta (Crimea) Conference (1945)................................................. Potsdam Declaration (1945).......................................................................................................... Japan’s First Instrument of

Surrender (1945)............................................................................. ~ in Chinese：日本投降書........................................................................................................... Surrender Order of the Imperial General Headquarters of Japan (1945).........

..................... Temporary Provisions Effective During the Period of the Communist Rebellion [full text] (1948)....................................................................................................................... ~ in Chinese: 動員戡亂時期臨時條款【全文】.................................

................................. Treaty of San Francisco (1951).................................................................................................... Treaty of Peace between the ROC and Japan (1952)................................................................ ~ in Chinese: 中華民國與

日本國間和平條約....................................................................... UN Resolution 2758 [full text] (1971)........................................................................................... Shanghai Communiqu? (1972)...............................................................

....................................... ~ in Chinese: 中華人民共和國和美利堅合眾國聯合公報（《上海公報》）................. Joint Communiqu? of the Gov. of Japan and the Gov. of the PRC (1972)........................... ~ in Chinese: 中日聯合聲明...................................................................................

.................. Taiwan Relations Act (1979).......................................................................................................... Joint Communiqu? of the PRC and the USA (1982)................................................................ ~ in Chinese: 中華人民共和國和美利堅合?國聯合公報（

八一七公報）................. PRC Constitution, Article 36: Religion (1982)............................................................................ ~ in Chinese: 中華人民共和國憲法（第三十六條）......................................................... UN Convention on the Law of the Sea (1982).....................

..................................................... The Sino-British Joint Declaration on the Question of Hong Kong (1984).......................... ~ in Chinese: 中華人民共和國政府和大不列顛及北愛爾蘭聯合王國政府 關於香港問題的聯合聲明...............................................................................................

.. Guidelines for National Unification [full text] (1991)................................................................. ~ in Chinese：國家統一綱領【全文】.................................................................................... ROC President Lee Teng-hui’s remarks about the “state-to-state rel

ationship” extant between the ROC and the PRC (1999)................................................................................ ROC President Chen Shui-bian’s “Five Noes” (2000, 2004).................................................... The “Anti-Secession Law” of the PRC [full text] (2005)..

.......................................................... ~ in Chinese：反分裂國家法【全文】.................................................................................... List of abbreviations and acronyms................................................................................................

..... Sources / Further reading..................................................................................................................... The Yellow River and the Yangtze River.......................................................................................... The Taiwan Area....

........................................................................................................................... Provinces (inset maps) Anhui安徽.................................................. Beijing北京................................................ Chongqing重慶........................

.................. Fujian福建.................................................. Gansu甘肅................................................. Guangdong廣東........................................ Guangxi廣西............................................. Guizhou貴州............................................. Hai

nan海南............................................... Hebei河北................................................. Heilongjiang黑龍江.................................. Henan河南................................................. Hong Kong香港........................................ Hubei湖北........................

.......................... Hunan湖南................................................. Inner Mongolia內蒙古............................. Jiangsu江蘇................................................ Jiangxi江西................................................ Jilin吉林...........................................

........... Liaoning遼寧............................................. Macau澳門................................................. Ningxia寧夏............................................... Qinghai青海............................................... Shaanxi陜西..............................................

Shandong山東........................................... Shanghai上海............................................. Shanxi山西................................................. Sichuan四川............................................... Taiwan台灣................................................ Tianjin天津...

............................................ Tibet西藏................................................... Xinjiang新疆.............................................. Yunnan雲南............................................... Zhejiang浙江............................................ History Yangshao and Lo

ngshan Cultures............ Shang/Yin.................................................... Western Zhou.............................................. The Seven Warring States......................... Qin................................................................ Western Han......................

.......................... Eastern Han................................................. The Three Kingdoms................................ China in 400 AD......................................... Sui................................................................. Early Tang......................

.............................. Late Tang..................................................... Northern Song........................................... Southern Song............................................. Yuan.............................................................. Ming..............

................................................ Qing.............................................................. Republic of China (ROC).......................... 　　Note：The maps are sketches created by the author for information and orientation purposes only. Minor inaccuracies cannot be comp

letely ruled out. Unless otherwise indicated, all maps are oriented with North at the top. Copyright for all maps ? Tilman Aretz. Table of contents 6

Nucleus Near-Infrared (nNIR) Irradiation of Single A549 Cells Induces DNA Damage and Activates EGFR Leading to Mitochondrial Fission

為了解決New Balance 1500的問題，作者MOMOH GBETUWA 這樣論述：

Abstract Background: There has been great interest in identifying the biological substrate for light-cell interaction and their relations to cancer treatment. In our study, a single cell nuclear NIR (nNIR) and cytosol exposed NIR has been used to determine for the first-time mitochondria fragmentat

ion count (MFC) to compare NIR effect on subcellular cells. Near infra-red (NIR) possesses less light scattering and absorption in biological tissues it has a biological window that bears a very small photodamage and thus possesses a deep tissue penetration depth. Aim: To evaluate near-infrared (NIR

) laser focused into the nucleus (nNIR) or cytoplasm (cNIR) of a single living cell by a high numerical aperture condenser to dissect the novel role of cell nucleus in mediating NIR effects on mitochondrial dynamics of A549 non-small cell lung cancer cells.Materials and Methods: Cultured 150 single

cell of A549 nucleus and cytosol were incubated with 0.3 μM mitotracker green for 30 min washed with PBS, imaged control cell then treated with 224.02 J/cm2 NIR for 10 s and cells imaged at different time points of 1, 5, 10, 15 and 20 min. A549 cells were treated with conjugated 100 nM FND-EGF and i

ncubated with PD153035, caffeine and cetuximab for 1 h, and imaged cells. Results: Our analysis showed nNIR, but not cNIR, triggered mitochondrial fission in 10 minutes. On the contrast, the fission/fusion balance of mitochondria directly exposed to cNIR does not change. While the same phenomenon is

also triggered by single molecular interactions between epidermal growth factor (EGF) and its receptor EGFR, pharmacological studies with cetuximab, PD153035 and caffeine suggest EGF signaling crosstalk to DNA damaging response to mediate rapid mitochondrial fission as a result of nNIR irradiation.

These results suggest that nuclear DNA integrity is a novel biological target for cellular response to NIR. Conclusions: These results suggest that nuclear DNA integrity is a novel biological target for cellular response to NIR. Keywords: Keywords: near infrared (NIR), epidermal growth factor recep

tor (EGFR), mitochondrial fragmentation count (MFC), mitochondrial dynamic, cetuximab, caffeine.